Anal cancer is on the rise in the United States. Men who have sex with men (MSM) and HIV-infected people have a higher risk of developing anal cancer compared to the general male population. Although the majority of anal cancers are caused by the human papillomavirus (HPV)--the same virus that causes cervical cancer--there is no official guidance that promotes routine screening for anal cancer. What can health center providers do to prevent anal cancer in their patients? In this webinar, Dr. Lori Panther reviews the basic epidemiology of HPV, and discusses the signs, symptoms, potential screening mechanisms, and prevention methods for anal cancer that providers can offer their patients.